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1 Even though this slowdown in gut motility is by design, it also may be the reason many people on GLP-1 medications experience some initial digestive disturbances and discomfort

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First introduced in 1927, insulin shock therapy was devised by Manfred Sakel, an Austrian neuropsychologist, after he observed an improvement in the psychiatric condition of one of his patients with a morphine addiction when he recovered from a hypoglycaemic coma accidentally induced by too much insulin

The post suggests raising storage integrity and formulation stability with the provider as possible contributing factors when clinical response plateaus unexpectedly

Frequently reported adverse effects include nausea, Diarrhea, constipation, stomach pain, and reduced appetite

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